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Direct evidence for GABAergic activity of Withania somnifera on mammalian ionotropic GABAA and GABA receptors

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Glutathione is a molecule that is present in every cell, where it works as a potent detoxifier and protector of cellular function

Concomitantly, water influx causes matrix swelling, rupture of the rigid OMM and release of apoptogenic proteins sequestered in IMS although, apoptotic cell death under MPT is inhibited due to energetic failure and ATP exhaustion and oxidative stress-mediated caspase inactivation