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147 Leptin binds to the leptin receptor (LepRb) and activates JAK2/STAT3 pathway to decrease body weight and normalizes blood glucose concentration, meanwhile, JAK2 stimulates the phosphorylation of insulin receptor substrate (IRS1/2), then activates PI3K/Akt pathway and directly affect insulin action

Limited evidence from animal studies suggests potential interactions with certain antibiotics

Compounding is the process of creating a custom medication tailored to a patients specific needs

If a patient is constantly nauseated, unable to eat properly, or feeling unwell, the medication may no longer be the right tool