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M.OrtegaA.MenaS.Antoni SirerolJ.ObradorE

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Tirzepatide for Weight Loss Maintenance Tirzepatide for maintenance of bodyweight reduction in people with obesity in the USA (SURMOUNT-MAINTAIN): a multicentre, double-blind, randomised, placebo-controlled trial, Lancet (2026) [PubMed abstract] BIBLIOGRAPHY 1 - Zepbound PI 2 - PMID 34170647 - Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes, NEJM (2021) 3 - PMID 35133415 - Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial, JAMA (2022) 4 - North Carolina Pharmacy Practice Act

Ipamorelin works through a separate ghrelin receptor pathway, telling the pituitary to release GH