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The FDA and other regulatory agencies have conducted extensive reviews of safety data from clinical trials and post-marketing surveillance

Ferulic acid in Chaihu Shugan San modulates depression-like behavior, endothelial and gastrointestinal dysfunction in rats via the Ghrl-Edn1/Mecp2/P-mTOR/VEGFA pathway: a multi-omics study

This dual action makes NAC particularly effective at supporting your body's antioxidant defenses

Both nutrients exert antidepressant effects through gut microbiota regulation, either by enhancing SCFA production or reducing inflammation, making them the most promising candidates for clinical translation (consistent with Sections 4.3, 5.3)