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Fragment ion tolerance was set to 30 ppm and precursor tolerance to 20 ppm, with one tryptic terminus per peptide and one peptide per protein established as prerequisites identification, and with up to two variable modifications per peptide permitted

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[11] Post-marketing surveillance and poison control data have highlighted risks associated with compounded semaglutide, particularly unintentional overdoses due to dosing errors, confusion with pen devices, or incorrect administration from unregulated sources