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Mutations in genes that regulate the cell cycle and DNA repair further suggested mechanisms of increased CNAs: a truncating insertion in FGFR1OP, which anchors microtubules 47 (patient CAS-D) and deleterious missense mutations in WRN, associated with homology-directed repair and stability of fragile sites 48 , in patients CAS-C, CAS-F and MI-F

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[1] [4] Never store Mounjaro in the freezer, and if a pen has been accidentally frozen, it must be discarded and not used, even if it has thawed

Normal human melanocyte homeostasis as a paradigm for understanding melanoma