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Electrolyte supplementation (sodium, potassium, magnesium) helps maintain proper hydration balance, particularly during the first few months when caloric intake drops most sharply

Subsequently, RVG peptide-guided exosomes were employed to deliver short interfering RNA to neurons, microglia, and oligodendrocytes in the brain by targeting the gamma-aminobutyric acid (GABA) receptor, inducing target gene knockdown with negligible nonspecific uptake in other tissues 35

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