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Wegovy standalone trials The STEP 1 trial (published in NEJM, 2021) enrolled 1,961 adults without type 2 diabetes and found that semaglutide 2.4 mg produced 14.9% average weight loss over 68 weeks, compared with 2.4% on placebo

ECW/TBW Ratio : Extracellular to total body water ratio

Patients should monitor their glucose levels more frequently during the first few weeks after discontinuation, especially if no alternative diabetes medication has been prescribed

Class B1 G protein-coupled receptors (GPCRs) play a crucial role in regulating physiological functions, particularly glucose homeostasis and mechanism of action in cardiometabolic syndrome