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Recent research highlights that environmental factors, such as ultraviolet (UV) radiation or chemical exposure, can trigger vitiligo by inducing the production of pathogen-associated molecular patterns (PAMPs) or damage-associated molecular patterns (DAMPs) ( + T cells target melanocytes, resulting in skin depigmentation

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Thus, the conjugation of resveratrol occurs within less than 30 minutes, limiting its half-life and consequently its prolonged systemic antioxidant effect [56]