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79 This upregulation correlates with obesity severity, adipocyte hypertrophy, and adverse glucometabolic status, reflecting a tightly regulated interplay between autophagy, tissue remodeling, and metabolic stress

Clustering and UMAP visualization were conducted on the merged dataset using 10 to 30 principal components and a resolution between 0.4 and 1.2 for the shared nearest neighbor clustering algorithm (depending on the respective dataset)

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