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1 H NMR (400 MHz, DMSO-d 6 ) = 5.82 (d, J = 6.1 Hz, 2H), 5.78 (d, J = 6.2 Hz, 2H), 2.84 (hept, J = 7.0 Hz, 1H), 2.09 (s, 3H), 1.20 (d, J = 6.9 Hz, 6H)

99-101 Some evidence suggests long-term berberine use, especially at high doses, may impair some aspects of cellular metabolism in specific types of cells