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Aggregating data from Table 3 reveals consistent cross-barrier alterations in cytokine levels in both CSF and peripheral blood across different clinical stages (first-episode/FES, acute/ASZ, and chronic/CSZ), which hold clinical translational significance: 1)

On the other end, adding only 0.5mL creates a 20mg/mL solution where tiny measurement errors translate to significant dosing inaccuracies