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Cell Metab (2019) 30(5):98796.e6

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Enhanced Keap1-Nrf2 signaling protects the myocardium from isoproterenol-induced pathological remodeling in mice

The analysts in a Tuesday note caveated that China-specific trials tend to generate less profound weight loss relative to global studies, primarily driven by lower BMI and higher proportion of male participants (though we recognize that the proportion of females was similar between HARBOR-1 and ATTAIN-1). After this data drop, Hengrui said it plans on submitting new drug applications (NDAs) in both obesity and type 2 diabetes in China, according to a Tuesday release