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Bryan Tysinger, a research assistant professor at USC who worked on the analysis, said there are two reasons

this can lead to dehydration and, in some cases, acute kidney injury maintain fluid intake and seek review if symptoms are prolonged or you notice reduced urine output or dizziness Severe abdominal pain , particularly if it radiates to the back or is accompanied by vomiting this may indicate pancreatitis, a rare but serious adverse effect associated with the GLP-1 drug class

Interestingly, the study did find that sublingual GSH led to slightly greater glutathione levels compared to NAC, but both did increase levels

By preventing oxidative stress, glutathione helps protect cellular DNA, proteins, and lipids from damage