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Regulation of GLP-1 and glucagon expression is primarily posttranscriptional, with differential cleavage of proglucagon by PC1/3 (encoded by proprotein convertase subtilisin/kexin type 1 [ PCSK1 ]) generating GLP-1, and by PC2 (encoded by PCSK2 ) to produce glucagon

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These side effects are generally short-lived and resolve on their own

Peptydy miedziowe trac stabilno w rodowisku o niskim pH poniej 5, dlatego unikaj jednoczesnego stosowania z czyst witamin C (kwas askorbinowy), retinolem w formie kwasu retinowego czy silnymi kwasami AHA/BHA, jak glikolowy lub salicylowy te skadniki mog spowodowa utlenianie miedzi i dezaktywacj tripeptydu