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For example, estrogen signaling has been shown to enhance the anorexigenic effects of GLP-1 RAs by modulating central pathways involved in food reward, which could account for the more pronounced weight loss observed in premenopausal women [49, 50]

The two most common culprits are: Iron: An iron deficiency can lead to anaemia, with profound fatigue, weakness, and shortness of breath being hallmark symptoms

Furthermore, based on preclinical evidence suggesting that muscle-derived IL-6 may enhance postprandial GLP-1 secretion [90], it has been proposed that GLP-1RAs could modulate metabolic and inflammatory processes through this pathway [39]

What symptoms should prompt me to contact my GP whilst taking a GLP-1 medicine