glp 1 drugs and bipolar disorder GLP-1 receptor activation linked to lower depression odds GLP-1 receptor agonists show promise

Kamoen V, Vander Stichele R, Campens L, De Bacquer D, Van Bortel L, de Backer TL

In addition to the high content of readily oxidizable molecules like catecholamines, and polyunsaturated fatty acids, and relatively lower antioxidant levels compared to other organs, these factors make the brain more vulnerable to oxidative stress

Local administration is commonly used because its effects appear strongest close to the target tissue

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