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Intracellularly, merlin regulates the growth factor receptor-induced activation of the small G proteins Ras and Rac, which in turn activate mitogen-activated protein kinase (MAPK) signaling [48, 51]
Figure 8 3.9 Translational validation of hub Se-ASRGs by drug prediction and experimental verification To analyze drug associations of hub Se-ASRGs, drug enrichment prediction and experimental analysis were performed
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Another Parkinsonian model employing 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) toxicity found that UA could reduce oxidative stress, inflammation, and dopaminergic neuronal dysfunction in the brain 35
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