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We selected DPP-4 inhibitors as the comparator because they are not associated with the outcome and are used at a similar disease stage to GLP-1 receptor agonists16827

Like all medications, GLP-1s like Ozempic come with potential side effects

In addition, proteomic studies highlight the complex interplay between depression and comorbid conditions such as diabetes, emphasizing the importance of accounting for a patients overall health status during diagnosis and treatment planning [448]