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NF-B inhibition: In general, carnitine has anti-inflammatory properties by inhibiting the activity of NF-B by provoking an increase in miR-373 (a microRNA that affects NF-B levels).[ref] Gut inflammation: In the intestines, acetyl-L-carnitine has been shown to improve gut inflammation

Such a mechanism could theoretical be mediated by the oncoprotein MDM2, which interacts with p53 but has recently also been found to associate with certain cell surface receptors and regulate their functions (Shenoy et al, 2001)

But each also requires more careful starting dose management