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In February this year, the Australian Crime Commission's report into drugs in sport lifted the lid on the widespread off-label use of substances

Lipids, fatty acids, and ketogenic amino acids In addition to the glucose metabolites explored above, several clinical trials and preclinical studies have revealed changes in lipid metabolism after TBI [30, 31]

The study also reported a substantial increase in adiponectin, a hormone that plays an important role in: Improving insulin sensitivity Supporting fat metabolism Promoting anti-inflammatory processes Among participants who had indicators of prediabetes at baseline, some of the groups receiving the two-drug combination experienced complete reversion to normoglycaemia, meaning all participants in those groups moved from a prediabetic state to normal blood glucose levels

In November 2024, CMS proposed a rule change that would have allowed Medicare Part D to cover drugs prescribed for weight loss to treat obesity, starting in 2026