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Professor of Medicine Boston University School of Medicine Copyright 2001-2026 Linus Pauling Institute Figure Alternative Text Figure 1

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It is essential for the formation of red blood cells and the proper development of the fetal neural tube during pregnancy, which is critical for preventing birth defects like spina bifida

Specifically, bioactive molecules such as leukotrienes and prostaglandins produced during AA metabolism via LOX and COX can directly or indirectly increase NOX complex activity, leading to the catalysis of intracellular ROS synthesis, including O , thereby participating in the regulation of oxidative stress and cell signalling pathways [15]