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PMID: 3583493

Here is a summary of the most commonly used DSIP dosing protocol based on available reports: Starting DSIP dose: 100mcg administered at night, preferably three hours before bedtime

Because it degrades in blood in a pathway involving amino-peptidases, it may not be suitable for people who take medications that inhibit or are metabolized by peptidases (e.g., captopril, a treatment for hypertension).4 Also, based on what we know about other therapeutic peptides, we would say DSIP is contraindicated for women who are pregnant or breastfeeding as well as people with a personal history of cancer