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to 80% silymarin

doi:10.1056/NEJMoa2301972 Sanyal AJ, Kaplan LM, Frias JP, et al

In early CKD patients, arginine and asymmetric dimethylarginine (ADMA) can reduce renal microvasodilation, impair normal glycolysis, regulate oxidative stress, and mediate the generation of reactive oxygen species (ROS), to maintain chronic inflammation in the body and generate renal albuminuria (19)