ZEB1 inhibition sensitizes cells to the ATR inhibitor VE-821 by abrogating epithelial-mesenchymal transition and enhancing DNA damage
Practical Application Polyphenol-rich foods: Pomegranates, cranberries, blueberries, green tea Prebiotic fibers: Garlic, onions, leeks, asparagus Omega-3 sources: Fatty fish, walnuts, flaxseeds, chia seeds Fermented foods: Yogurt, kefir, sauerkraut, kimchi Avoid excessive antibiotics: When possible, preserve gut bacteria diversity Limit artificial sweeteners: May negatively impact beneficial bacteria Regular exercise: Supports beneficial bacterial populations Adequate sleep: 7-9 hours supports microbiome balance Strategy 4: Fatty Acid Signaling for L-Cell Activation The Science: L-cells express receptors that detect specific fatty acids in the intestinal lumen
At TrimBody M.D., we focus on keeping your protein levels right and doing weekly check-ins
NAD+ itself doesn't absorb well orally because of its molecular weight, which explains why most supplements contain precursors like nicotinamide riboside
