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Based both on the oddity of non-metazoans having this isoform and the intimate intracellular interaction between these intracellular protozoan parasites and both their vertebrate and invertebrate metazoan hosts, lateral gene transfer from host to parasite seemed a plausible model for the appearance of this unexpected isoform outside of metazoans

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doi: 10.1371/journal.pone.0053657 17 KernJ

Several sex effects were also observed throughout these studies, where despite higher levels of total plasma acylcarnitines in females compared to males, in aging females, there was a significant decrease in total acylcarnitines which was not seen in aging males, indicating that aging may impact female peripheral lipid bioenergetics more than males