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Description

Journal of Obesity & Metabolic Syndrome (2021) 9

No significant differences in hematological or serum biochemical parameters were observed between any treatment group and the control group (Additional file 2: Tables S8S9)

Despite this, there are growing concerns over its serious side effects, including blood clots, DVTs, and pulmonary embolisms

Previous melanocortin agonists that failed clinical trials for general obesity share common features that constrain their therapeutic windows, including low receptor potency, poor safety profiles, and suboptimal pharmacokinetics