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J Clin Endocrinol Metab 2020;105:dgz047.PubMed 49

Blood sugar fluctuations, changes in appetite, digestive discomfort, and possible effects on brain chemistry all play a role

Menten AI in Toronto applies machine-learning-guided protein design to create peptides with desired pharmacological properties, leveraging structure-based modeling for binding affinity and metabolic stability

Risk factors that predispose to development of the condition include female sex (preferentially metabolise acetaminophen to sulfated derivatives) malnutrition, sepsis, diabetes, underlying liver disease and pregnancy