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This observation serves as evidence of successful loading of GSH onto the surface of CS NPs

The results indicated that BA exhibited a protective role in rats against the haematological perturbations, body weight changes as well as primary and secondary arthritic lesions induced by CFA (doses 2, 5, and 10 mg kg 1 day 1 , p.o.) with remarkable reduction in the rheumatoid factor and C-reactive protein (CRP), which are distinct serum markers of arthritis and inflammation

Superoxide combines with NO to form peroxynitrite that oxidizes BH 4 and destabilizes eNOS to produce more superoxide 22, 24, 25 thus, further enhancing the development of oxidative stress

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