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Overall, the effects of Ser/Gly/Thr metabolism on macrophage polarization are mainly mediated by changes in one-carbon metabolic flux, methyl donor availability, and redox homeostasis, and the resulting outcome is often manifested as threshold regulation of inflammatory transcriptional programs and alterations in phenotypic stability

From boardroom discussions in pharma companies to kitchen-table conversations in Indian households, GLP-1 drugs are not just changing prescriptionsthey are changing perspectives