In mouse models, dietary Li deficiency accelerates A deposition, tau phosphorylation, microglial reactivity, synaptic and myelin loss, and memory decline
Monotherapy with the once weekly GLP-1 receptor agonist dulaglutide for 12 weeks in Japanese patients with type 2 diabetes: dose-dependent effects on glycaemic control in a randomised, double-blind, placebo-controlled study
By kinetic analysis of single, double, and triple mutants, as well as from studies of reaction products, it was established that the enzyme A216H catalyzes the hydrolysis of the thiol-ester substrate by a mechanism that includes an acyl intermediate at the side chain of Y9
It also plays a big role in liver detoxification, helping the body flush out alcohol, heavy metals, and toxins from the environment