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The STEP 4 trial (Rubino et al., JAMA, 2021) similarly showed roughly 6.9% regain over 48 weeks in those who stopped, versus continued loss in those who kept taking semaglutide

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15 The study found that GLP-1 medication was associated with an 18% relative reduction in risk of developing any AMD from no AMD at baseline: 0.46% of the GLP-1 group had any AMD after 10 years, while 0.55% had any AMD in the control group