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Manson JE, Chlebowski RT, Stefanick ML, et al

When examining a composite cardio outcomes endpoint (death from CV disease, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for unstable angina), the ELIXA trial suggested that GLP-1s did not increase cardiovascular event risk (hazard ratio of 1.02)

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first-in-human IV PK: Goldstein AL et al