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Abstract Recent large clinical trials on sodium-glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists, with the aim of verifying cardiovascular safety, have revealed that these medications have a preventative advantage on adverse cardiovascular outcomes, including worsening of heart failure and deterioration of nephropathy, in patients with type 2 diabetes (T2D)

Excluded studies included fewer than six patients using AID systems, excluded studies comparing AID with non-insulin glucose lowering medications, and excluded studies that did not report glycemic outcomes

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