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The STEP UP programme examined weight loss results among participants who took the 2.4 mg per week dose and those who took the 7.2 mg per week dose over a 72-week period

Methods Ethics statement Our study protocol was reviewed and approved by the Institutional Review Board of Chung Shan Medical University Hospital (CS2-24100

By analyzing and comparing the risks and benefits of different dietary patterns, we have developed a stepwise nutritional intervention strategy based on MD for the auxiliary treatment of different types of OA patients and emphasized the importance of comprehensive intervention (physics and medication) in the treatment of OA