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This system operates through several mechanisms, including direct scavenging of reactive species, metal chelation, and enzymatic processes that rapidly neutralise reactive molecules following their formation (126, 243, 256)

Meta-analyses suggest that RT interventions increase aortic and carotid artery stiffness in healthy young men in an intensity dependent mannersuch that higher intensities (75%80% of 1RM) yield greater increases in central arterial stiffness (Kawano et al., 2006

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Additionally, castration considerably decreased the expression of important antioxidant enzymes (AOEs) (GPx1, thioredoxin, SOD2, and peroxiredoxin 5) and markedly increased the expression of ROS-generating NAD(P)H oxidases