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It improves mitochondrial mass and the number of autophagic vesicles in renal tubular cells, while its active ingredients can have an effect on nutrient-sensitive signalling pathways, and can play a role in protecting the kidneys by activating mitophagy nutrient-sensing mitochondrial pathways ( Yishen capsule consists of five herbs, which modulate silent information regulator sirtuin 1 (SIRT1) and acetylated nuclear factor kappa-light-chain-enhancer of activated B cells(NF-kB) p65, increase the expression of SIRT1, LC3-II, and Beclin-1 in vitro and in vivo , thereby enhancing the autophagy process in podocytes through the SIRT1/NF-B pathway, ultimately ameliorating DN ( San-Huang-Yi-Shen capsule (SHYS) has demonstrated clinical efficacy in reducing urinary albumin levels in patients with DN, markedly enhancing renal function and mitigating renal pathological damage, with early intervention proving to be significantly more effective ( Danzhi Jiangtang Capsule(DJC)is a traditional Chinese medicine formula, which consists of five Chinese medicines: Radix Pseudostellariae,Radix Rehmanniae, Cortex Moutan, Rhizoma Alismatis,Semen Cuscutae Chinensis and Leech

Improved Metabolism: Supports energy balance by regulating blood sugar levels

Methyltransferases catalyze the methylation of Sterigmatocystin to O-methylsterigmatocystin