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Abstract Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by itching, epidermal barrier dysfunction, and an unbalanced inflammatory reaction

However, during fasting, NHR-49 and other key regulators of lipolysis and -oxidation appear dispensable for lifespan extension

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FAKPaxillin Cascade Western blot analysis confirmed dose-dependent increases in phosphorylation of both FAK and paxillin, correlating with enhanced fibroblast migration and F-actin formation (Chang et al., Journal of Applied Physiology, 2011).