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Apart from these functions, glutathione has also been linked to skin health and pigmentation control, leading to its popularity as a skin lightening agent
Impairment of Nrf2/ARE signaling has been observed in HCV infection, leading to elevated ROS levels that can activate autophagy and facilitate HCV maturation and release 103,104
High AST/ALT ratio may indicate advanced alcoholic liver disease rather than heavy drinking
(5) Adverse effects and management: Cholinergic muscarinic effects such as diarrhea, abdominal cramping, and increased salivation are common and may be managed with agents such as propantheline or loperamide
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