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Importance of a holistic approach to diabetes and weight management Maintaining muscle mass is one important factor of a successful weight loss journey, and is also helpful for improving blood sugar control

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Instead, other anti-diabetic agents not belonging to GLP-1RA class, including metformin, might only have an indirect effect on GLP-1 pathway and on PDAC stroma preventing cancer development through different mechanisms, mainly harnessing PDAC cancer cells [80]