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In the future, it will be necessary to examine how Sirt1 regulates the Shh/Gli-1 signaling pathway and to confirm the results of the present study in vivo

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A large preclinical toxicity program run across mice, rats, rabbits, and dogs found BPC-157 well tolerated with no serious treatment-related toxicity, no identifiable lethal dose, and no genotoxic or teratogenic signal, which is the strongest safety data point available by Xu 2020

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