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MelnykSFuchsGJSchulzELopezMKahlerSGFussellJJet al
Functional activation of DCs stimulates NK-cells, promotes an increase in proinflammatory cytokines (IL-12, IL-6, IL-23, IL-1) and a decrease in antiinflammatory transforming growth factor- (TGF-1), which control adaptive reactions, which contributes development of Th1 and Th17, IL-17-producing T cells and cytotoxic T cells
Research focuses on its ability to upregulate the expression of vital tight-junction proteins (such as claudins, occludins, and zonula occludens-1), thereby minimizing luminal permeability while simultaneously boosting local mucus synthesis and stimulating vitamin D3 receptor expression
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