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Interestingly, injecting mice with 400 ng of recombinant mouse IL-6 twice daily for 7 days significantly increases fasting plasma active GLP-1, as well as ileal Gcg and Pcsk1 mRNA, but not plasma GLP-2 (ELISA) or DPP4 activity (Ellingsgaard et al., 2011)

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Timing: Preferably before a meal

Taking the moral thing aside of, does everyone deserve a miracle drug if it exists, even if there is no economics around it, it might just be ROI positive for Medicare to do this if everyone's going to need knee replacements, hip replacements, Diabetes treatment, amputations, and cardiovascular interventions