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ROS also interact with unsaturated fatty acids in phospholipids, and aldehydes such as 4-hydroxynonenal, 4-hydroxyhexanal, acrolein, and MDA are the most reactive compounds (169)

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Similarly, reusing needles or syringeseven on the same vial for the same patientsignificantly increases infection risk and can introduce particulate matter or dulled needles that damage the rubber stopper, creating a pathway for contamination