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Mechanistically, Semaglutide and Liraglutide are both glucagon-like peptide-1 (GLP-1) receptor agonists, but Semaglutide has been modified to have a longer half-life and increased binding affinity, potentially contributing to its greater weight loss efficacy

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Summary of Next Steps If leg cramps are affecting your quality of life while taking Mounjaro, follow these steps: Evaluate your fluid intake: Increase water and add electrolytes immediately