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Participants taking semaglutide demonstrated a 26% reduction in the composite endpoint of heart attack, stroke, or cardiovascular death compared to placeboindependent outcomes that correlate with improved lipid profiles

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Major incretins such as GLP-1 and GIP can control appetite by reducing feelings of hunger and by increasing satiety and have a regulatory effect on glucose homeostasis through the reduction of blood glucose levels and insulin release ( Figure 1 ) (Edholm et al., 2010