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Does the failure of any of these metabolic branches and nodes contribute to the induction of ferroptosis in organ damage and degenerative diseases beyond their roles in cancer

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Unlike somatic cells, which possess a variety of DNA repair pathways to correct oxidative damage, spermatozoa have only one active DNA repair enzyme, 8-oxoguanine DNA glycosylase (OGG1), which is responsible for repairing oxidative base lesions (73, 74)

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