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Absence of Common Growth Hormone Side Effects: Because AOD-9604 does not bind to growth hormone receptors or elevate IGF-1, it avoids edema and fluid retention, joint pain and stiffness, carpal tunnel syndrome, glucose elevation and insulin resistance, increased cancer risk concerns from IGF-1 elevation, organ growth or acromegaly features with long-term use, and thyroid function suppression
One should consider the primary phase lesion and hemorrhaging that results from mechanical damage during SCI as well as the secondary phase lesion that lasts several hours or even several months and is accompanied by edema, hemorrhage, inflammation, and cytotoxic edema [44,45,46,47] and may extend to the white matter area and lead to white matter degeneration and damage [48, 49]
Cysteine oxidation produces disulfide bonds, sulfenic acid, sulfinic acid, and ultimately sulfonic acid
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