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ROS are continuously produced by the body due to immunological reactions, mitochondrial bioenergetics, and oxidative metabolism

315 Soluble fibre and modest amounts of dietary fat may help slow nutrient absorption and reduce glycaemic variability, though tolerance should be individualised and guided by dietitian review

Conclusion and perspectives: towards a systems-level understanding of proteostasis Over the past decade, proteostasis research has evolved from studying isolated degradation pathways to appreciating a deeply interconnected, adaptive, and dynamic cellular defense network