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CXCR4 inhibition attenuates calcium oxalate crystal deposition-induced renal fibrosis

Dexrazoxane (ICRF-187) is used clinically to attenuate the cardiotoxic effects of certain anticancer drugs (e.g., doxorubicin)

Several genes related to the complement system, including the gene of complement factor H (CFH) [416], age-related maculopathy susceptibility 2 (ARMS2) [417], and others, have been identified as risk factor for AMD